Evaluation of Antioxidant and Antibacterial Activities of Different Solvent Extracts of Quince Furit and Leaf


  • Gulnur Arabaci Department of Chemistry, Faculty of Science and Arts, Sakarya University, Serdivan-Sakarya 54187, Turkey
  • Inam Muayad Abdulmaged Al-Sabbagh Department of Chemistry, Faculty of Science and Arts, Sakarya University, Serdivan-Sakarya 54187, Turkey


Quince antioxidant, DPPH, ferrous ion chelating, reducing power, antibacterial


This study aims to determine the antioxidant and antibacterial effects of quince (Cydonia oblonga) and quince leaf extracts grown in Sakarya and used in the treatment of various diseases with various solvents. Dried quince and leaves were extracted with ethanol, acetone, and ethyl acetate solvents, and their antioxidant activity was determined with three different methods. These methods are; DPPH free radical removal activity, iron ion chelating, and reduction capacity methods. As a result of the experiments; among the tested substances, the highest DPPH activity in ethanol was determined as 95.282% (±0.01) with quince fruit substance. The highest activity of quince fruit substance in acetone with a value of 68.250% (±0.01) in its capacity to chelate iron (II) Ions. The highest reducing capacity ratio among ethyl acetate extracts was determined as 3.91 mg/mL of quince leaf extract. In addition, the antibacterial properties of the quince and leaves were determined by the agar well diffusion method against E.coli, B. Cereus and S. aureus bacteria. According to the results obtained, the material of the quince fruit showed effective antibacterial properties against all bacteria, the diameters of which ranged from 10 to 20 mm, and the material of the quince leaf, the diameters of which ranged from 18 dec19 mm. The highest quince fruit ratio in acetone solution is 16 mm zone diameter found against B. Cereus, while its highest ratio is 20 mm zoned against E.coli.


. Mandal S., Yadav S., Yadav S. ve Nema, R.K., 2009. Antioxidants: A Review, Journal of Chemical and Pharmaceutical Research, 1, 1, 102-104.

. Lushchak V., 2014. Free radicals, reactive oxygen species, oxidative stress and its classification, Chemico- Biological Interactions., 224, 164–175.

. Commoner B., Townsend J., Pake G. E., 1954. Free radicals in biological materials. Nature., 174(4432):689–691.

Halliwell B., Gutterıdge JMC., “Role Of FreeRadicals and Catalytic Metal Ions in Human Disease: AnOverview.” In: Methods inEnzymology,186, 1-85, 1990.

. Tsao R. ve Deng Z., 2004. Separation Procedures For Naturally Occurring Antioxidant Phytochemicals, Journal of Chromatography B, 812, 85-99

. Halliwell B., Cross C.E. ve Gutteridge J.M.C., 2002. Free Radicals, Antioxidants, and Human Disease. Where are We Now?, Journal of Laboratory and Clinical Medicine,119, 598-620

. Pillai C.K., Pillai K.S., 2002 Antioxidants in health. Indian J Physiol Pharmacol.,46(1):1-5.

. Koleva I.I., van Beek T.A., Linnsen J.P.H., de Groot A. ve Evstatieva, L.N., 2002. Screening of Plant Extracts for Antioxidant Activity: A Comparative Study of Three Testing Methods, Phytochemical Analysis. 13, 8-17.

. Wettasinghe M. ve Shahidi F., 1999. Antioxidant and Free Radical-Scavenging Properties of Ethanolic Extracts of Defatted Borage (Borago officinalis L.) Seeds, Food Chemistry, 67,4, 399-414.

. Janovska D. Kubikova K, Kokoska L 2003. Screening for Antimicrobial Activity of Some Medicinal Plants Species of Traditional Chinese Medicine. Czech J. Food Sci. 21: 107-110.

. Oliveira, P. A., Pereira, J. A., Andrade, P. B., Valenta, P., Seabra, M. R. and Silva, B. M. 2008. Organic acids composition of Cydonia Oblonga Miller leaf. Food Chem., 111,393-399.

. Vinson, J. A., Su, X., Zubik, L. and Bose, P. 2001. Phenol antioxidant quantity and quality in foods: fruits. J. Agric. Food Chem., 49, 5315-5321.

. Vaez, H., Hamidi, S., and Arami, S. (2014). Potential of Cydonia oblonga leaves in cardiovascular disease. Hypothesis 12, 1–10.

. Silva, B. M., Andrade, P. B., Ferreres, F., Domingues, A. L., Seabra, R. M. and Ferreira, M. A. 2002a. Phenolic profile quince fruit (Cydonia oblonga Miller) (Pulp and Peel). J.Agric. Food Chem., 50, 4615-4618.

. Moreira, R., Chenlo, F., Torres, M.D. and Vallejo, N. 2008. Thermodynamic analysis of experimental sorption isotherms of loquat and quince fruit. J. of Food Eng., 88,514-521.

. Brand-Williams, W., Cuvelier, M. E., Berset, C., 1995. Use of a free radical method to evaluate antioxidant acitivity, Lebensmittel-Wissenschaft undTechnologie/Food Science and Technology, 28, 25-30.

. Oyaizu M., 1986. Studies on product of browning reaction prepared from glucose amine, Japan Journal of Nutrition, 44, 307- 315.

. Valgas C., De Souza S.M., Smânia E.F.A., 2007. Screening methods to determine antibacterial activity of natural products. Braz. J. Microbiol. 2007;38:369–380.

. Balouiri M, Sadiki M, Ibnsouda S.K. 2016. Methods for in vitro evaluating antimicrobial activity: A review. JPA. 6: 71-79.

. Muzykiewicz A., Zielonka-Brzezicka J., Klimowicz A., 2018. Quince (Cydonia oblonga Mill.) as a useful source of antioxidants – antioxidant activity evaluation, Herba Polonica, 64, 4, 23-33.

. Wojdyło A., Oszmiański J., Bielicki P., 2013. Polyphenolic composition, antioxidant activity, and polyphenol oxidase (PPO) activity of quince (Cydonia oblonga Miller) varieties. J Agric Food Chem; 61:2762-72.




How to Cite

Gulnur Arabaci, & Inam Muayad Abdulmaged Al-Sabbagh. (2022). Evaluation of Antioxidant and Antibacterial Activities of Different Solvent Extracts of Quince Furit and Leaf . International Journal of Natural Sciences: Current and Future Research Trends, 13(1), 52–60. Retrieved from https://ijnscfrtjournal.isrra.org/index.php/Natural_Sciences_Journal/article/view/1076